Brain Inflammation Tied to Agitation, Irritability in Alzheimer’s

In JAMA Network Open, Tharick Pascoal and his team showed that mood changes in Alzheimer’s originate from brain inflammation, not amyloid plaques or tau tangles. The findings suggest that therapies that reduce inflammation may be helpful.

Here are some news stories about the study:

Health Day: Brain Inflammation May Trigger Alzheimer’s-Linked Anger, Anxiety

Journal of Healthcare Contracting: Irritability, agitation and anxiety in Alzheimer’s patients caused by brain inflammation, study says

WPXI: Pitt study links symptoms like irritability, anxiety in Alzheimer’s patients to brain inflammation

McKnights Long-Term Care News: Brain inflammation plays role in irritability, anxiety in people with Alzheimer’s